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National
Institutes of Health, NIAAA Senior
Research Fellow 1997-2000
U.S.
Department of Agriculture Research
Associate 1995-1997
North
Carolina State University Breeding
& Genetics Ph.D. 1990-1993
Universidad Nacional Agraria Breeding
& Statistics M.S. 1981-1983
Universidad Nacional Agraria Agronomy B.S. 1981
Professional
History
Pennsylvania
State University Assistant
Professor
2000-
National
Institutes of Health, NIAAA Senior
Research Fellow 1997-2000
U.S.
Department of Agriculture Research
Associate 1995-1997
University
of Florida Postdoctoral
Fellow 1993-1994
North
Carolina State University Research
Assistant 1990-1993
International
Potato Center
Associate
Geneticist 1983-1990
Honors and Awards
1996-Outstanding Research: QTL
mapping for Marek’s disease in chickens.
ARS, USDA. East Lansing, MI.
1993-Excellence Doctoral
Research, North Carolina State
University, Raleigh,
NC.
1991-Honor Society Pi Alpha XI, Iota Chapt. North
Carolina State University,
Raleigh, NC.
1980-First Class Honors, B.S.
Agronomy. Universidad
Nacional Agraria. Lima, Peru.
Current Research Interest
I am interested in elucidating the molecular genetic basis of
variation for common complex diseases using positional cloning, gene
expression profiling via DNA chip technology and statistical and
computational genomics tools. I
search for quantitative trait loci (QTL) and eventually the allele variants
that explain most of the variation for mammary inflammation induced by E. coli using mouse models of
disease.
Research
Experience
Genome-wide
scan for genes affecting vulnerability to alcoholism and other related
personality disorders in Finnish pedigrees. Section on Population Genetics
& Linkage, Laboratory of Neurogenetics,
NIAAA, NIH. Bethesda, MD.
1997-2000.
Genetic
mapping of QTL affecting susceptibility to Marek’s
disease in chickens. Avian Disease and Oncology Laboratory, ARS, USDA. East
Lansing, MI. 1995-1997.
Genetic
engineering of tomatoes for resistance to Tomato Mottle Virus using microprojectile bombardment and Agrobacterium-mediated
transformation systems. Gulf
Coast Res. and Education
Center, University
of Florida. Bradenton,
FL. 1994.
Genetic
resistance to Potato Viruses X and Y and trichome-mediated
resistance to virus spread in hybrid Solanum phureja x S. stenotomum
diploid Potatoes, Ph.D. Thesis. North Carolina State University. Raleigh, NC. 1990-1993.
Genetic
improvement of potato populations for adaptation to temperate and tropical
climates. Breeding & Genetics Department, International Potato Center. Lima, Peru. 1983-1990.
Selected
Publications
Radel, M.,
R.L. Vallejo, N. Iwata, J.C. Long, R. Aragon, M. Virkkunen,
and D. Goldman. 2004. Haplotype-based localization of an alcohol dependence gene to
the 5q33 GABAA gene cluster. Arch. Gen. Psychiatry, Accepted.
Vallejo,
R.L., Y.L. Li, G.W. Rogers, and M.S. Ashwell. 2003. Genetic diversity and
background linkage disequilibrium in the North American Holstein
cattle population. J. Dairy Sci. 86:4137-4147
Vallejo, R.L. 2003. Power to detect loci linked
to common diseases of dairy cattle using identical-by-descent based methods
of half-sib pair linkage analysis. J. Anim. Sci. 81:160 (Suppl. 1)
Goldman, D., M. Radel, and R. Vallejo. 2001.
Alcoholism candidate alleles and haplotypes in the
gaba-serotonin domain. Internat. Behav. & Neur.
Genet. Soc. http://www.ibngs.org/SanDiego/goldman.html
Iwata, N., R.L. Vallejo, M. Virkkunen,
J.C. Long, T. Suizuki, N. Ozaki, and D. Goldman.
2001. Evidence for linkage of genetic variants at the serotonin 2B receptor
gene (HTR2B) with Finnish alcoholics. Biol.
Psychiatry 49(8):563 (Suppl. S)
Radel, M., R. Vallejo, R. Aragon, J.C. Long, M. Virkkunen, and D. Goldman. 2001. Analysis of GABAA
receptor subunit genes in alcohol dependence and obsessive-compulsive disorder.
Am. J. Hum. Genet. 69(4):576 (Suppl.)
Radel, M.,
R.L. Vallejo, N. Iwata, R. Aragon, H. Naukkarinen,
M. Virkkunnen, J.C. Long, and D. Goldman. 2000. Linkage
and association analyses of sequence variants of the GABRA6, GABRB2 and
GABRG2 gene cluster and alcohol dependence in a Finnish sample. Am. J. Hum. Genet. 67(4):222 (Suppl. 2)
Vallejo,
R.L., J. Brooks, J. Lappalainen, D. Hoopes, T.B. High, L.A.
Wilhelm, M. Virkkunen, M. Linnoila,
D. Goldman, and J.C. Long. 1999. Multi-point linkage of antisocial
alcoholism to 5-HT1B receptor gene on chromosome 6 in two populations. Alcohol. Clin.
Exp. Res. 23(5):58A (Suppl.)
Bergen,
A.W., L. Wilhelm, R.L. Vallejo, S. Kim, D. McKeane,
R. Robin, D. Goldman, and J.C.
Long. 1999. Association between alcohol dependence and 5-locus haplotypes on chromosome 11p15.5 in an American Indian
population. Am. J. Hum. Genet. 65(4):69
(Suppl.)
Vallejo,
R.L., L.A. Wilhelm, D. Hoopes, T. High, M. Virkkunen,
M. Linnoila, D. Goldman, and J.C. Long. 1998. Genome-wide
search for genes affecting vulnerability to alcohol dependence in Finnish
pedigrees. Am. J. Hum. Genet. 63(4):236
(Suppl.)
Goldman D.,
J. Lappalainen, R.L. Vallejo, R.W. Robin, M. Virkkunen, M. Linnoila, and
J.C. Long. 1998. Linkage of the
5HT1B serotonin receptor to antisocial alcoholism in Finns and Southwestern
Indians. Am. J. Med. Genet.
81(6):479
Vallejo,
R.L., J.C. Long, D. Hoopes, M. Virkkunen, D. Goldman, and M. Linnoila.
1998. Autosomal
genome scan for loci linked to alcohol dependence and related psychiatric
disorders in Finnish pedigrees. Alcohol.
Clin. Exp. Res. 22(3):97A (Suppl.)
Vallejo,
R.L., L.D. Bacon, H.C. Liu, R.L. Witter, M.A.M. Groenen,
J. Hillel and H.H. Cheng. 1998. Genetic mapping of quantitative
trait loci affecting susceptibility to Marek’s
disease virus induced tumors in F2 intercross chickens. Genetics 148:349-360
Xu, S.Z.,
N. Yonash, R.L. Vallejo, and H.H. Cheng. 1998. Mapping quantitative trait loci for
binary traits using a heterogeneous residual variance model: An application
to Marek’s disease susceptibility in
chickens. Genetica
104:171-178
Vallejo,
R.L., G.T. Pharr, H.C. Liu, H.H. Cheng, R.L. Witter, and L.D. Bacon. 1997. Non-association between Rfp-Y major histocompatibility
complex-like genes and susceptibility to Marek’s
disease virus-induced tumors in 63 x 72 F2
intercross chickens. Anim. Genet. 28:331-337
Pharr,
G.T., R.L. Vallejo, and L.D. Bacon. 1997. Identification of Rfp-Y (Mhc-like)
haplotypes in chickens of Cornell lines N and P. J. Hered.
88:504-512
Cheng,
H.H., I. Levin, R.L. Vallejo, H. Khatib,
J.B. Dodgson, L.B. Crittenden, and J. Hillel. 1995. Development of a genetic map of the
chicken with markers of high utility. Poult. Sci.74:1855-1874.
Smith,
E.J., H.H. Cheng, and R.L. Vallejo. 1995. Mapping functional chicken genes: an
alternative approach. Poult. Sci. 75:642-647
Teaching Activities (Penn State University)
GENET/STAT/ANSC 597F Statistical Genomics: QTL Mapping in
Natural Populations, 2002-03
ANSC 322 Principles of Animal Breeding, 2002
ANSC 590 Colloquium Animal Sciences, 2000-02
Guest Lecturer, Honors ANSC
001 Animal Science, 2001-2002
Guest Lecturer, ANSC 297B Introduction to Animal Biotechnology,
2001-03
Guest Lecturer, ANSC 597B Foundation Readings in Animal Science, 2001-02
Scientific
and Academic Activities
U.S.
Multist. Res. Proj.
NC-1010 Interpret. cattle
genomic data: biology, applicat. & outreach,
2003 -
U.S.
Multist. Res. Proj.
NE-112 Mastitis resistance to enhance
dairy food safety, 2003 -
U.S.
Multist. Res. Proj.
NC-209 Genetic improv.
of cattle using molec.
genetic information, 2000-02
Grant Reviewer, United
States-Israel Binational Agric. Research and Development
Fund, 2002 –
Grant Reviewer, The Israel
Science Foundation, 2004-
Faculty, Graduate Degree
Program in Animal Science, Penn State
University, 2000 -
Faculty, Inter-College
Graduate Degree Program in Genetics, Penn
State University,
2000 -
Faculty, Center for Genome
Studies, Penn State
University, 2000 -
Ad Hoc Reviewer, Journal of Dairy Science, 2000 -
Ad Hoc Reviewer, Genetic Epidemiology, 1999
Book Reviewer, Analysis of
Molecular Marker Data, Joint Plant Breeding Symposia Series, Oregon
State University,
Corvallis, 5-6 August 1994, Wehner (ed.), 1995
American Association for the Advancement of Science
American Dairy Science Association
American Society of Animal Science
Genetics Society of America
Congress
and Workshops
The 53rd Annual Amer. Soc. Hum. Genet.
Meeting, Los
Angeles, CA, November 4-8, 2003
From
genome to disease: symp. of high throughput biol., NHLBI, NIH, Bethesda, MD, July 23-24, 2003
Meeting of Amer. Dairy Sci.
Assoc. & Amer. Soc. of Animal Sci., Phoenix, AZ, June 22-26, 2003
Plant & Animal Genome XI, San Diego, CA, January 11-15, 2003
Meeting of Amer. Dairy Sci.
Assoc. & Amer. Soc. of Animal Sci., Indianapolis, IN, July 24-28, 2001
Course on Genetics
Computer Group Sequence Analysis, CIT, NIH, Bethesda, MD, January 7-9, 1999
Scientific Meeting of Res. Soc. on Alcoholism, Santa
Barbara, CA, June 26-July 1, 1999
The 48th Annual Amer. Soc. Hum. Genet.
Meeting, Denver, CO, October 27-31, 1998
Scientific Meeting of Res. Soc. on Alcoholism, Hilton Head Island, SC, June 20-25, 1998
Training Course on C Language Fundamentals, CIT, NIH, Bethesda, MD, April 20-24, 1998
Training Course on Getting Started with C Language, CIT, NIH, Bethesda, MD, March 30-April 2, 1998
Meeting on Genetic
architecture of complex traits, NIGMS, NIH, Bethesda, MD, December 10-11, 1997
The 47th Annual Amer. Soc. Hum. Genet.
Meeting. Baltimore, MD, October 28 - November 1, 1997
The 6th Annual Meeting of Internat. Genet. Epidemiology Soc., Baltimore, MD, October 27-28, 1997
Gordon Res. Confer. on Quantitative Genetics and Biotechnology, Ventura, CA, February 9-14, 1997
Plant & Animal Genome V, San Diego, CA, January 12-16, 1997
The 25th Internat.
Congress on Animal Genetics, Tours, France, July 20-25, 1996
Training Course on Computational Genomics, Cold Spring Harbor, NY, November 1-6, 1995
Biotechnology’s
role in genetic improv. of farm animals, USDA, Beltsville, MD, May 14-17, 1995
Professional
References
Ashwell, Melissa S., Ph.D., Assist. Professor,
Dept. of Animal Science, North Carolina
State University,
Box 7621, Raleigh,
NC 27695-7621.
Phone (919)513-7488, email: Melissa_Ashwell@ncsu.edu
Barbato, Guy F., Ph.D., Assoc. Professor, Dept.
of Poultry Science, Penn State University, 201 Henning Bldg, University
Park, PA 16802. Phone: (814)865-4481, Email: gfb1@psu.edu
Brooks,
Philip J., Ph.D., Acting Chief, Section of Molecular Neurobiology,
Laboratory of Neurogenetics, National
Institute on Alcohol Abuse & Alcoholism, NIH, 12420
Parklawn Dr.,
Rm.411, Bethesda, MD
20892. Phone: (301)496-7920. Email: pjbrooks@mail.nih.gov
Cheng, Hans H., Ph.D.,
Res. Geneticist, Avian Disease & Oncology Lab., ARS, USDA, 3606
E. Mount Hope Rd., East Lansing, MI 48823. Phone: (517)337-6758, Email: hcheng@pilot.msu.edu
Eisen, Eugene J., Ph.D., Professor, Dept.
of Animal Science, North Carolina State University, Box 7621, Raleigh, NC
27695-7621. Phone: (919)515-4017, Email: gene_eisen@ncsu.edu
Enoch, Mary-Anne, M.D., Ph.D.,
Staff Scientist, Section of Human Neurogenetics,
Laboratory of Neurogenetics, National Institute
on Alcohol Abuse & Alcoholism, NIH, 12420 Parklawn
Dr., Rm.451, Bethesda, MD 20892. Phone: (301)496-2727. Email: me53z@NIH.GOV
Goldman, David, M.D., Ph.D.,
Acting Chief, Section of Human Neurogenetics,
Laboratory of Neurogenetics, National Institute
on Alcohol Abuse & Alcoholism, NIH, 12420 Parklawn Dr., Rm.451, Bethesda,
MD 20892.
Phone: (301)443-0059, Email: dg7q@nih.gov
Long, Jeffrey C., Ph.D., Professor, Dept. of Human Genetics &
Center for Statistical Genetics, University of Michigan Medical School, 4909
Buhl, Ann Arbor, MI 48109-0618. Phone: (734)763-3385, Email: longjc@umich.edu
Rogers, Gary W., Ph.D., Professor, Dept. of Animal Science,
University of Tennessee, 201D McCord Hall, Knoxville, TN 37996-4500. Phone:
(865)974-7289, Email: grogers2@tennessee.edu
Weir, Bruce S., Ph.D., Professor, Dept. of Statistics, North
Carolina State University,
Box 8203, Raleigh,
NC 27695-8203.
Phone: (919)515-3574, Email: weir@stat.ncsu.edu
Weiss, Kenneth M., Ph.D., Evan Pugh Professor of Biological
Anthropology & Genetics, Dept. of Anthropology, Penn State University,
523 Carpenter Building, University Park, PA 16802. Phone: (814)865-0989, Email: kmw4@psu.edu
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